Cerebellar disorders
Localising cerebellar signs, sorting causes of ataxia by tempo, the emergencies of cerebellar stroke and Wernicke, and the paraneoplastic and genetic ataxias.
Tier 1Condition
Written with AI assistance and fact-checked against the sources below. For exam study, not clinical decisions. How notes are made
At a glance
- The cerebellum coordinates movement. Lesions cause ataxia, dysarthria, nystagmus and intention tremor, on the same side as the lesion.
- The vermis controls the trunk and gait; the hemispheres control the ipsilateral limbs.
- Sort the causes by tempo: minutes (stroke, haemorrhage), days to weeks (toxic, inflammatory, paraneoplastic, Wernicke), years (alcohol, degenerative, genetic).
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Sources
- Therapeutic Guidelines: Neurology; Toxicology and Toxinology (Wernicke encephalopathy, thiamine)AU/NZTherapeutic Guidelines Limited (eTG complete), current eTG edition (version not verified)
- Skyclarys (omaveloxolone) Australian public assessment reportAU/NZTherapeutic Goods Administration, AusPAR published June 2026
- Omaveloxolone (Skyclarys): Public Summary Document, November 2025 PBAC meetingAU/NZPharmaceutical Benefits Advisory Committee, November 2025
- Guidelines for the Treatment of Alcohol Problems: preventing and treating Wernicke's encephalopathyAU/NZAustralian Government Department of Health (Haber et al.), 2021
- 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhageAmerican Heart Association and American Stroke Association (Stroke), 2022
- Updated diagnostic criteria for paraneoplastic neurologic syndromes (Graus F et al. Neurol Neuroimmunol Neuroinflamm 2021;8:e1014)Neurology Neuroimmunology and Neuroinflammation, 2021
- Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia (Cortese A et al. Nat Genet 2019;51:649-658)Nature Genetics, 2019
- Last updated
- 14 November 2026
What changed
- 14 November 2026 Personal emails, About story and Australian-style copy