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Neurology

Unusual stroke syndromes

Brainstem and thalamic syndromes that are easy to miss, and the uncommon causes of stroke in younger adults (dissection, venous thrombosis, RCVS, CADASIL, moyamoya, vasculitis, Fabry disease), with the test and first treatment for each.

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At a glance

  • Two groups are tested: brainstem and thalamic syndromes that don't look like a typical stroke, and uncommon causes of stroke, especially in people under 50.
  • Posterior circulation strokes are missed more often than anterior ones. Vertigo, diplopia, reduced consciousness and ataxia can be the only signs.
  • In young stroke, think dissection, PFO, venous thrombosis, RCVS, drugs (methamphetamine), antiphospholipid syndrome and genetic arteriopathy. The standard work-up and reperfusion are in Ischaemic stroke.

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Last updated
14 November 2026
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