Acute rheumatic fever and rheumatic heart disease
The Australian Jones criteria for high-risk and low-risk groups, benzathine benzylpenicillin prophylaxis and how long to give it, echo diagnosis, and RHD in pregnancy and remote communities.
Tier 1Condition
Written with AI assistance and fact-checked against the sources below. For exam study, not clinical decisions. How notes are made
At a glance
- ARF is an autoimmune reaction to group A streptococcal (Strep A) infection of the throat and, in northern Australia, probably the skin. RHD is the valve damage left behind, mostly from recurrent episodes.
- Australia has some of the highest recorded rates in the world, nearly all in Aboriginal and Torres Strait Islander people, along with Māori and Pacific Islander people and migrants from endemic countries. Overcrowded housing and poor access to washing facilities drive transmission.
- Diagnosis uses the Australian Jones criteria, which are more sensitive for high-risk groups than the international version.
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Sources
- Australian guideline for the prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease (Edition 3.4, October 2026)AU/NZRHDAustralia (Menzies School of Health Research), Edition 3.4, October 2026
- WHO guideline on the prevention and diagnosis of rheumatic fever and rheumatic heart diseaseWorld Health Organization, 2024
- Rwebembera J, Marangou J, Mwita JC et al. 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease. Nat Rev Cardiol 2024;21:250-63World Heart Federation (Nature Reviews Cardiology), 2023
- Beaton A, Okello E, Rwebembera J et al. Secondary antibiotic prophylaxis for latent rheumatic heart disease (GOAL). N Engl J Med 2022;386:230-40New England Journal of Medicine, 2022
- Connolly SJ, Karthikeyan G, Ntsekhe M et al. Rivaroxaban in rheumatic heart disease-associated atrial fibrillation (INVICTUS). N Engl J Med 2022;387:978-88New England Journal of Medicine, 2022
- 2025 ESC/EACTS Guidelines for the management of valvular heart diseaseEuropean Society of Cardiology and European Association for Cardio-Thoracic Surgery, 2025
- Last updated
- 14 November 2026
What changed
- 14 November 2026 Turnstile bot check on sign-in and signed-out feedback