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Infectious diseases

Acute testicular pain and epididymo-orchitis

Torsion until proven otherwise, and surgery without waiting for ultrasound. Epididymo-orchitis is usually chlamydia or gonorrhoea in sexually active men and enteric organisms after instrumentation; ceftriaxone plus doxycycline for 14 days covers the STI causes.

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At a glance

  • Testicular torsion is a surgical emergency. Suspect it in any sudden severe testicular pain, especially under 25, and send to theatre without waiting for imaging.
  • Epididymo-orchitis is the most common cause in adults. In sexually active men it is usually chlamydia or gonorrhoea; after instrumentation, anal sex or a UTI, think E. coli and other enteric organisms.
  • Empirical treatment (ASHM): ceftriaxone 500 mg IM plus doxycycline 100 mg twice daily for 14 days. Change to cover enteric organisms when urine culture or history points that way.

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Last updated
14 November 2026
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