Acute testicular pain and epididymo-orchitis
Torsion until proven otherwise, and surgery without waiting for ultrasound. Epididymo-orchitis is usually chlamydia or gonorrhoea in sexually active men and enteric organisms after instrumentation; ceftriaxone plus doxycycline for 14 days covers the STI causes.
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At a glance
- Testicular torsion is a surgical emergency. Suspect it in any sudden severe testicular pain, especially under 25, and send to theatre without waiting for imaging.
- Epididymo-orchitis is the most common cause in adults. In sexually active men it is usually chlamydia or gonorrhoea; after instrumentation, anal sex or a UTI, think E. coli and other enteric organisms.
- Empirical treatment (ASHM): ceftriaxone 500 mg IM plus doxycycline 100 mg twice daily for 14 days. Change to cover enteric organisms when urine culture or history points that way.
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Sources
- Australian STI Management Guidelines for use in primary care: Epididymo-orchitisAU/NZASHM, Accessed November 2026
- Therapeutic Guidelines: Antibiotic. Epididymo-orchitisAU/NZTherapeutic Guidelines Limited (eTG complete), 2025 to 2026 staged update (topic version not verified)
- 2024 European guideline on the management of epididymo-orchitis (Justice et al.)IUSTI, Journal of the European Academy of Dermatology and Venereology, 2024 guideline; J Eur Acad Dermatol Venereol 2026;40(2):166-73
- EAU Guidelines on Paediatric Urology: acute scrotumEuropean Association of Urology, Current edition, accessed November 2026
- Last updated
- 14 November 2026
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